{"id":954,"date":"2026-05-01T14:40:00","date_gmt":"2026-05-01T11:40:00","guid":{"rendered":"https:\/\/lista-avocati.ro\/blog\/?p=954"},"modified":"2026-05-02T11:48:27","modified_gmt":"2026-05-02T08:48:27","slug":"ordinul-nr-1-076-789-2026-publicat-in-m-of-nr-358-bis-din-30-aprilie-2026-emis-de-ministerul-sanatatii-si-casa-nat","status":"publish","type":"post","link":"https:\/\/lista-avocati.ro\/blog\/ordinul-nr-1-076-789-2026-publicat-in-m-of-nr-358-bis-din-30-aprilie-2026-emis-de-ministerul-sanatatii-si-casa-nat\/","title":{"rendered":"Ministerul S\u0103n\u0103t\u0103\u021bii anun\u021b\u0103 schimb\u0103ri majore \u00een protocoalele terapeutice oficiale"},"content":{"rendered":"

CE S-A MODIFICAT<\/h3>\n

Ordinul nr. 1.076\/789\/2026 (publicat \u00een M.Of. nr. 358 bis din 30 aprilie 2026), emis de Ministerul S\u0103n\u0103t\u0103\u021bii \u0219i Casa Na\u021bional\u0103 de Asigur\u0103ri de S\u0103n\u0103tate, modific\u0103 anexele nr. 1 \u0219i 2 la Ordinul nr. 564\/499\/2021 privind protocoalele terapeutice.<\/p>\n

Modific\u0103rile concrete (art. I din ordin):<\/p>\n

  • Abrogate<\/strong>: protocoalele de la pozi\u021biile nr. 137 cod (L01XC02) \u0219i nr. 338 cod (L04AC07) \u2014 pct. 1 din anex\u0103<\/li>\n
  • Ad\u0103ugate<\/strong>: 33 de noi pozi\u021bii (nr. 396\u2013428), dup\u0103 pozi\u021bia 395 \u2014 pct. 2 din anex\u0103<\/li>\n
  • \u00cenlocuite integral<\/strong> cu protocoale noi: Agalsidasum Beta (poz. 8, cod A014E), Agalsidasum Alfa (poz. 39, cod A16AB03), Miglustatum (poz. 46, cod A16AX06), Migalastatum (poz. 50, cod A16AX14) \u2014 pct. 3, 4, 5, 6 din anex\u0103<\/li>\n

    –<\/p>\n

    CE \u00ceNSEAMN\u0102 PRACTIC<\/h3>\n

    Protocoale actualizate pentru boli rare:<\/strong><\/p>\n

  • Agalsidasum Beta<\/strong>: doz\u0103 de 1 mg\/kg corp, perfuzie intravenoas\u0103 la fiecare 2 s\u0103pt\u0103m\u00e2ni (26 administr\u0103ri pe an); posibil\u0103 administrare la domiciliu dac\u0103 medicul curant aprob\u0103; durata tratamentului \u2014 indefinit\u0103<\/li>\n
  • Agalsidasum Alfa<\/strong>: doz\u0103 de 0,2 mg\/kg o dat\u0103 la dou\u0103 s\u0103pt\u0103m\u00e2ni, perfuzie de 40 de minute; eligibili pacien\u021bi de la v\u00e2rsta de 7 ani; durata \u2014 indefinit\u0103<\/li>\n
  • Miglustatum<\/strong> (Gaucher tip I): 100 mg de trei ori pe zi; pentru Niemann-Pick tip C, doze ajustate \u00een func\u021bie de suprafa\u021ba corporal\u0103 (adul\u021bi \u226512 ani: 200 mg de trei ori pe zi)<\/li>\n
  • Migalastatum<\/strong>: 123 mg (1 capsul\u0103) o dat\u0103 la dou\u0103 zile; contraindicat la pacien\u021bi cu rat\u0103 de filtrare glomerular\u0103 estimat\u0103 mai mic\u0103 de 30 ml\/min\/1,73 m\u00b2; administrare pe stomacul gol (repaus alimentar minim 4 ore)<\/li>\n

    Monitorizarea principal\u0103 r\u0103m\u00e2ne la fiecare 6 luni<\/strong> pentru parametri renali, cardiovasculari, neurologici.<\/p>\n

    –<\/p>\n

    CINE E AFECTAT<\/h3>\n
  • Pacien\u021bi cu boal\u0103 Fabry<\/strong>, boal\u0103 Gaucher tip I<\/strong> (u\u0219oar\u0103\/moderat\u0103), boal\u0103 Niemann-Pick tip C<\/strong><\/li>\n
  • Medici prescriptori din specialit\u0103\u021bile: nefrologie, cardiologie, genetic\u0103 medical\u0103, neurologie, pediatrie, medicin\u0103 intern\u0103, gastroenterologie, hematologie<\/li>\n
  • Casa Na\u021bional\u0103 de Asigur\u0103ri de S\u0103n\u0103tate<\/strong> \u2014 prin impactul asupra programelor na\u021bionale de s\u0103n\u0103tate \u0219i contractelor cost-volum<\/li>\n

    –<\/p>\n

    CE TREBUIE F\u0102CUT<\/h3>\n

    | Ac\u021biune | Termen |
    \n|–|–|
    \n| Aplicarea noilor protocoale pentru prescrierea Agalsidasum Beta, Alfa, Miglustatum, Migalastatum | Imediat, de la publicare (30 aprilie 2026) |
    \n| Reevaluarea pacien\u021bilor trata\u021bi cu medicamente de la pozi\u021biile abrogate: L01XC02 \u0219i L04AC07 | Imediat |
    \n| Monitorizarea pacien\u021bilor conform noilor grile (parametri la 6 luni) | Continuu |
    \n| Evaluare anual\u0103 pentru pacien\u021bii care nu<\/strong> beneficiaz\u0103 de tratament specific | Continuu |<\/p>\n

    Termen de aplicare<\/strong>: Ordinul se aplic\u0103 de la data public\u0103rii \u00een Monitorul Oficial \u2014 30 aprilie 2026<\/strong> (art. II din ordin).<\/p>\n\n

    Analiz\u0103 generat\u0103 automat din Monitorul Oficial \u2014 50.ro AI Platform.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

    CE S-A MODIFICAT Ordinul nr. 1.076\/789\/2026 (publicat \u00een M.Of. nr. 358 bis din 30 aprilie 2026), emis de Ministerul S\u0103n\u0103t\u0103\u021bii \u0219i Casa Na\u021bional\u0103 de Asigur\u0103ri de S\u0103n\u0103tate, modific\u0103 anexele nr. 1 \u0219i 2 la Ordinul nr. 564\/499\/2021 privind protocoalele terapeutice. Modific\u0103rile concrete (art. I din ordin): Abrogate: protocoalele de la pozi\u021biile nr. 137 cod (L01XC02) … Cite\u0219te mai mult<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,16],"tags":[],"class_list":["post-954","post","type-post","status-publish","format-standard","hentry","category-ghiduri-juridice","category-monitorul-oficial"],"_links":{"self":[{"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/posts\/954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/comments?post=954"}],"version-history":[{"count":4,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/posts\/954\/revisions"}],"predecessor-version":[{"id":1002,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/posts\/954\/revisions\/1002"}],"wp:attachment":[{"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/media?parent=954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/categories?post=954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lista-avocati.ro\/blog\/wp-json\/wp\/v2\/tags?post=954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}